Presented at the 79th ASRM Scientific Congress & Expo, Shady Grove Fertility’s research team evaluates the association between saline-infused sonograms (SIS) during intrauterine inseminations (IUI) and pregnancy outcomes.

ROCKVILLE, Md. [October 17, 2023] – New research from Shady Grove Fertility (SGF), a US Fertility practice, assures fertility patients who have undergone a saline-infused sonogram (SIS) that they can proceed with intrauterine insemination (IUI) in the same cycle and expect comparable pregnancy rates as if they had waited for another cycle.  
“As one of the only private practice fertility centers in the nation to employ a full-time dedicated research team, our top priority is conducting research that makes a difference in the lives and treatment plans of our patients,” shares Phillip A. Romanski, M.D., M.Sc.,  fertility specialist at SGF New York and SGF Research Director. “This new study can provide data for our patients that can help them move forward with fertility treatment more quickly in their IUI cycles. We know that fertility treatment is a time commitment, and we can now feel confident about giving time back to our patients with an evidence-based method.”  

The retrospective cohort study, Evaluating the Association Between Saline-Infusion Sonogram (SIS) during an Intrauterine Insemination (IUI) Cycle and Pregnancy Outcome, was conducted by SGF physicians Kate Devine, M.D.; Benjamin S. Harris, M.D., M.P.H.; and Phillip A. Romanski, M.D., M.Sc.; and US Fertility’s Samad Jahandideh, Ph.D.; alongside SGF’s Jiarui Wang, M.S.; and UC Davis Medical Center Sacramento resident, Adriana J. Wong, M.D., M.P.H.,.  
The research evaluated 6,321 IUI cycles – 351 patients who had an SIS in the same cycle and 5,970 patients who had the SIS within a four-month time frame before the cycle. Data gathered from the study suggested that performing uterine cavity evaluation with SIS during a patient’s first IUI cycle was not associated with a significant difference in clinical pregnancy rates or ongoing pregnancy rates. Further, pregnancy rates remained similar for patients with an SIS during the IUI cycle compared to patients with an SIS performed within a period of four months preceding their IUI treatment. 

Learn more about Shady Grove Fertility’s research team, which conducts and publishes high-quality research studies to advance the field of reproductive medicine to provide the most up to date, and evidence-based care for patients. 

About Shady Grove Fertility (SGF)
SGF is a leading fertility and IVF center of excellence with more than 100,000 babies born from 30+ years of continuous innovation and patient-centered fertility care. With convenient locations throughout the U.S. and in Santiago, Chile, SGF accepts most insurance plans and makes fertility treatment accessible and affordable through innovative financial solutions, including 100% refund guarantees for eligible patients. SGF is a proud partner practice of US Fertility, the largest physician-owned and physician-led partnership of top-tier fertility practices nationally. Call 1-888-761-1967 to schedule a new patient appointment or visit for more information. 

About US Fertility 
US Fertility, the nation’s largest partnership of physician-owned and physician-led top-tier fertility practices, along with Ovation Fertility, a national network of premier IVF laboratories, are united under a shared mission to deliver the joy of parenthood through advanced reproductive medicine and innovative science. To date, US Fertility and Ovation Fertility practices have helped more than 225,000 individuals and couples build their families using assisted reproductive technology. US Fertility supports over 200 physicians by leveraging collective expertise, driving innovation, and by providing advanced business and digital solutions that streamline and enhance the delivery of exceptional patient care. Together with a growing suite of life science services, US Fertility is expanding access to the highest quality reproductive health care across over 100 clinic locations and 32 IVF laboratories. Visit for more information.