Presented at the 79th ASRM Scientific Congress & Expo, Shady Grove Fertility’s research team offers reassurance for intended parents growing their family with the help of an egg donor and can provide guidance on next steps for intended parents who require a replacement lot of donor eggs.

ROCKVILLE, Md. [October 19, 2023] – New research from Shady Grove Fertility (SGF), a US Fertility practice, conducted with Donor Egg Bank USA (DEBUSA) shows high pregnancy rates among intended patients who needed a replacement lot of donor eggs.   

 “Growing a family with the help of an egg donor is one of the many ways we make parenthood possible for our patients,” shares Kate Devine, M.D., Director of Research at SGF and Medical Director and Chief Research Officer at US Fertility. “Our new research can help provide reassurance for intended parents that parenthood is still possible even when the first round of donor egg treatment did not result in an embryo suitable for transfer.”  

The study, It’s Not One Strike and You’re Out: High Clinical Pregnancy Rate Among Recipient Couples Who Needed a Replacement Lot of Vitrified Donor Eggs, was conducted by SGF physicians Kate Devine, M.D., and Jeanne E. O’Brien, M.D., alongside Rush University Medical Center Chief Resident Amalia Namath, M.D., and DEBUSA’s director of embryology, Wayne Caswell, M.S. 
The research team looked at all intended parents using fresh or frozen sperm who required a replacement lot of donor eggs from DEBUSA from 2018 – 2022, which included 61 recipients. Patients qualified for a replacement if they failed to have at least one blastocyst suitable for transfer. For patients using a replacement lot, 66% successfully achieved a clinical pregnancy.  

“Seeing such a high rate of successful pregnancies among recipients after an unsuccessful donor egg cycle is an encouraging statistic,” shares Dr. O’Brien. “Recipients need reassurance to contemplate proceeding with another egg thaw cycle. The clinical evidence supports additional attempts with the same sperm source.”  

About Shady Grove Fertility (SGF)
SGF is a leading fertility and IVF center of excellence with more than 100,000 babies born from 30+ years of continuous innovation and patient-centered fertility care. With convenient locations throughout the U.S. and in Santiago, Chile, SGF accepts most insurance plans and makes fertility treatment accessible and affordable through innovative financial solutions, including 100% refund guarantees for eligible patients. SGF is a proud partner practice of US Fertility, the largest physician-owned and physician-led partnership of top-tier fertility practices nationally. Call 1-888-761-1967 to schedule a new patient appointment or visit for more information. 

About US Fertility 
US Fertility, the nation’s largest partnership of physician-owned and physician-led top-tier fertility practices, along with Ovation Fertility, a national network of premier IVF laboratories, are united under a shared mission to deliver the joy of parenthood through advanced reproductive medicine and innovative science. To date, US Fertility and Ovation Fertility practices have helped more than 225,000 individuals and couples build their families using assisted reproductive technology. US Fertility supports over 200 physicians by leveraging collective expertise, driving innovation, and by providing advanced business and digital solutions that streamline and enhance the delivery of exceptional patient care. Together with a growing suite of life science services, US Fertility is expanding access to the highest quality reproductive health care across over 100 clinic locations and 32 IVF laboratories. Visit for more information.