Melissa A. Esposito, M.D.

Board Certified Board Certified

  • Obstetrics and Gynecology
  • Reproductive Endocrinology and Infertility
Patient Testimonial
Dr. Esposito helped us fulfill our dreams of becoming parents. We will definitely be back when we’re ready for baby #2.

During our very first appointment with Dr. Esposito, she listened to our hopes, dreams, and frustrations. Even after the office closed, she continued to work out a plan for us.

Dr. Esposito and the entire SGF team was dedicated to helping us start our family. They truly made the experience painless and we now have a beautiful little boy because of them!

In less than a year we were finally pregnant and now have a beautiful daughter! The entire staff at SGF are amazing and we wish we would have went sooner.

I went through a tough journey, totaling 3 IUIs and 4 IVFs, but wouldn’t have traded any of that long and tough battle because we ended up with terrific twin sons!

Dr. Esposito gave me confidence during my infertility journey when other doctors shot me down. I am now back to try for a second child, and I feel really hopeful under Dr. Esposito’s care.

I recommend Dr. Esposito and SGF to everyone that I know struggling with fertility and will go back myself when we are ready for another baby.

Dr. Esposito and her team helped us conceive our son in 2014, and our daughter in 2016. I remember she even called me on a Saturday to discuss our treatment plan!

Dr. Esposito treated me so much nicer than just numbers on a scale. Thank you for that! It’s not often that you happen upon such kindness.

Working in the health field myself, I know it is not always easy to work with clients who are under such emotional stress. You and your team touched our hearts deeply.


Melissa A. Esposito, M.D., earned her medical degree from the University of Medicine and Dentistry of New Jersey and completed her residency training in obstetrics and gynecology from the University of Connecticut Health Center. She completed a 3-year fellowship program in reproductive endocrinology and infertility at the University of Pennsylvania. She is board certified in obstetrics and gynecology and reproductive endocrinology. Dr. Esposito is a member of the American Society for Reproductive Medicine and the American Congress of Obstetricians and Gynecologists.

Throughout her career, Dr. Esposito has been the recipient of numerous awards and honors from the American Medical Women’s Association, the Philadelphia Area Reproductive Endocrine Society, and the American Association of Gynecologic Laparoscopists, among others. Aside from her clinical practice, Dr. Esposito is also actively involved in teaching the medical students at Georgetown University School of Medicine in the department of obstetrics and gynecology, Division of Reproductive Endocrinology and Infertility.

Read More

I am always inspired by patients who persevere in their quest to become parents, when that goal can seem so difficult, yet remain optimistic and kind through it all!


  • Residency: Obstetrics and Gynecology, University of Connecticut Health Center
  • Fellowship: Reproductive Endocrinology and Infertility, University of Pennsylvania
  • Castle Connolly’s Top Doctors, 2024 
  • American Congress of Obstetricians and Gynecologists
  • American Society for Reproductive Medicine
  • Esposito MA, Coutifaris C, Barnhart KT. A moderately elevated day 3 FSH level has limited predictive value, especially in younger women. Hum Reprod. 2002;17(1):118-123.
  • Esposito M, Barnhart KT, Coutifaris C, Patrizio P. The role of peri-ovulatory LH during ART cycles stimulated exclusively with recombinant FSH. Fertil Steril. 2001;75(3):519-24.
  • Barnhart KT, Coutifaris C, Esposito M. The pharmacology of methotrexate. Expert Opinion in Pharmacotherapy. 2001;2(3):409-17.
  • Esposito M, and Patrizio P. Double follicular aspiration can save an IVF cycle after improper administration of hCG. J Reprod Med. 2000;45(6):511-14.


When I was in medical school and made my final decision to do my residency in obstetrics and gynecology, I had the opportunity to do a rotation with the REI department during my fourth year of medical school. The faculty was so amazing, as were the fellows that I got to shadow and work with, that I became inspired to go into the field. I loved the fact that as infertility specialists we make such a huge and positive impact in our patients’ lives, while getting to practice medicine in a field that is always dynamic, exciting, and continuously evolving.

I’ve been fortunate enough to have been inspired by many people in my life who have positively affected me in many ways! I’ve been inspired by exemplary teachers and mentors during my medical training, but especially during my subspecialty training, who through their dedication to this field and their patients demonstrated what being a great doctor really means! I’m also inspired by those in my life who give back to society through philanthropic and charitable acts of great kindness and sacrifice, by serving and helping the less fortunate, because like them, I believe strongly that we are all called to give back to society in some fashion. I have been inspired by my parents, who have bestowed upon me my steadfast work ethic and drive and sacrificed so much to be sure that I was able to get to college and medical school. I am always inspired by patients who persevere in their quest to become parents, when that goal can seem so difficult, yet remain optimistic and kind through it all!

I feel that we strive to always give the best patient care and practice very ethical medicine, in a field where that can be challenging and at times fraught with ethical dilemmas.

I have many destinations on my travel bucket list that I’m waiting to see until I retire because they will require a long visit. I also sponsor a classroom of children in India from the slums who attend a private school that is funded by corporate and private sponsors. I went to meet my children and their families last year and it was one of the best trips I’ve ever been on! I would love to be able to go to the school every year and volunteer for a month or so once I retire because I was so impressed with the school, the children, and the wonderful educators who have dedicated their lives to these children! These children are so happy and so smart, but more importantly so grateful for the chance to be able to attend school and improve their lives. Being even a small part of something so special makes me a better person!

When I know that a patient is struggling, I think it’s important to acknowledge and validate that they are struggling. I think it’s important to acknowledge that what they’re feeling is not unusual. I let them know that I understand that they are having a difficult time and to reiterate that I am here for them and will do what I can to help them. Just taking an extra few minutes during the consult, sending a card, or giving the patient a call goes a long way!