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Premature Ovarian Failure

The Basics

The Basics

Premature ovarian failure is the medical term used to describe early menopause. Menopause usually occurs in women between the ages of 42 and 56. Premature ovarian failure is a condition in which menopause occurs before the age of 40. Women who develop early menopause usually have run out of eggs in their ovaries.

Symptoms of Premature Ovarian Failure

You may experience menstrual irregularity, hot flashes, mood changes, loss of libido, and vaginal dryness.

Causes of Premature Ovarian Failure

The cause of premature ovarian failure is generally unknown. However, there are a few reasons why the ovaries may experience a decrease in egg supply at an early age. If a woman has been exposed to certain medications or medical treatments, such as chemotherapy or radiation therapy, this can damage or destroy the ovaries. Other probable causes include autoimmune diseases. A family history of early menopause can also play a role as some genetic conditions lead to premature failure of the ovaries. Women with premature ovarian failure are also more likely to have thyroid disease and diabetes.

Medical Contribution: Stephen Greenhouse, M.D. and Lauren Roth, M.D.


diagnostic tests for premature ovarian failure

Your medical history is important in diagnosing premature ovarian failure. However, your physician may need other tests to confirm the diagnosis such as:

Follicle-stimulating hormone (FSH)
A high level of follicle-stimulating hormone in your blood at a specific time in your cycle may indicate menopause.

Immunology testing
Tests that diagnose autoimmune problems of the thyroid, parathyroid, and adrenal gland that may be related to developing early menopause.

A photograph of your chromosomes, used to diagnose genetic causes of early menopause.


treatment for premature ovarian failure

While we cannot reverse the effects of premature ovarian failure there are still several treatment options to help aid in conception. Depending on the size of the remaining supply of eggs your physician may recommend either in vitro fertilization (IVF) using either your own eggs or donated eggs. While success may be possible using your own eggs, the best results will come when using the eggs of a donor.

When a decrease in ovarian supply is identified early, a woman may want to consider the Egg Freezing Program at Shady Grove Fertility as it provides a reliable option for the future. By freezing your eggs before the egg supply is nearly depleted, you can extend your fertility potential for when you are ready to have a family. However, women with diagnosed premature ovarian failure are not eligible for egg freezing.



Are there any long-term risks associated with early menopause?
Your ovaries are not producing enough estrogen to protect you from heart disease and osteoporosis (loss of bone density). You can reduce your risks for these diseases with hormone replacement therapy, calcium supplements, and regular exercise.

If you have other questions or would like to schedule an appointment, please contact our New Patient Center at 1-877-971-7755 or complete this brief online form.

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