Egg Freezing Cycle Timeline

Medical Contribution by: Sunita Kulshrestha, M.D.

After completing ovarian reserve testing, the physician consultation, and deciding to move forward with egg freezing, patients work with their physician and nursing team to determine a timeline of when to start an egg freezing cycle. From birth control to the actual freezing of the eggs, the egg freezing cycle is comprised of 5 main steps:

  1. Birth Control: 2-3 Weeks
    Birth control pills are used to help follicles grow at the same rate, but can also help with scheduling flexibility. We can also use birth control pills to manipulate when the patient wants her ovarian stimulation and egg retrieval to be. Upon selecting a retrieval week, we can work backwards to select a start date.
  2. Egg Freezing Cycle Day 1: 10-12 Days, 6-9 Monitoring Appointments
    Upon the start of your menstrual cycle, or after stopping birth control pills, patients will initiate daily injectable medications of the natural hormones FSH and LH. The medications are higher doses of hormones that replicate the natural hormones your body produces to mature one egg. Our goal is to stimulate the growth and development of a large number of eggs to freeze than what your body would do naturally. During this time, patients come to SGF for regular monitoring appointments, which include bloodwork and an ultrasound to ensure that follicles are growing appropriately and to change medication dosage, if necessary. This is about a 10 minute appointment that can be scheduled as early as 7:00 a.m. at many of the 29 SGF offices. This enables patients to go to work as normal without disrupting your day. Because the medications are natural, there are no unique side effects; but because the ovaries are becoming larger, there may be abdominal discomfort or bloating. Similarly, estrogen levels are increased, so the patient may experience heightened PMS symptoms.
  3. The Trigger Injection
    At the end of the stimulation period, the patient will be instructed to take a “trigger” injection. The trigger injection helps the eggs mature, and prepare for the egg retrieval.
  4. Egg Retrieval
    Two days following the trigger injection, the patient goes to one of SGF’s procedure centers for the egg retrieval. This intra-vaginal procedure takes place while the patient is under IV sedation, so they are asleep and pain-free. Even though the procedure is relatively quick, because of the anesthesia, it is required that someone is available to drive the patient home. This is the only day the patient misses work.
  5. Freezing of the Retrieved Eggs
    Once retrieved, embryologists evaluate the eggs to determine which ones are mature and freeze only the mature eggs. Eggs are frozen using vitrification, an ultra-rapid cooling process, and are then stored in liquid nitrogen for long-term storage. The patient is contacted the following day to let her know how many eggs were frozen. Two weeks later, the patient can expect to have her period.

On average, each egg freezing patient completes two egg freezing cycles to reach the recommended number of eggs. Not every egg will result in a pregnancy when couples try to conceive on their own, and the same truth applies when you freeze your eggs. Thus, we recommend that women 37 or younger who have excellent ovarian reserve function freeze between 15 to 20 mature eggs. For women over 38, or women at any age with diminished ovarian function, we recommend freezing 25 to 30 eggs. This provides the patient with multiple attempts to conceive if unsuccessful.

To learn more about the egg freezing cycle timeline or schedule an appointment, please contact our New Patient Center at 1-877-971-7755 or complete this brief online form