Nanette Santoro, M.D.

Board Certified Board Certified

  • Obstetrics and Gynecology
  • Reproductive Endocrinology and Infertility
Patient Testimonial
Dr. Mitchell is a gem for Shady Grove Fertility. She is very thorough in explaining the complex world of fertility, which I love as I can better make informed decisions. The beautiful thing is, she’s an advocate with you and for me, that makes all the difference in this journey.

I loved both the staff (pleasant and thoughtful) and Dr. Davis who is informative, gentle, and understanding. If you’re considering treatment I wouldn’t hesitate to come here.

Dr. Alexis Gadson is a treasure and very knowledgeable. She really put my husband and my mind at ease and this was just our first appointment with her. I’m truly thankful for her already!

I would highly, highly recommend Dr. O’Hern! Throughout my struggles with infertility, she has been kind, supportive, thoughtful, and determined to help me achieve a pregnancy. The staff at SGF, both in Clear Lake and the Medical Center, are amazing to work with!

Working with Dr. Kallen and his entire team was an absolute pleasure. They took time in designing a medical plan specific to our situation. Dr. Kallen never gave up on us and constantly reassured us at every step of the way to a successful pregnancy! We are very grateful for Dr. Kallen the SGF team!

Dr. Healy is so kind and selfless she is one of the kindest people that I’ve ever met. I definitely recommend her for any fertility treatments that people may need. We would never choose anyone else to handle our care. If you were looking for a fertility doctor, she is, hands-down, the best.


Nanette Santoro, M.D., completed her medical training in the 6-year B.S.-M.D. program at Rensselaer Polytechnic Institute and Albany Medical College, followed by residency at Beth Israel Medical Center in New York City and a fellowship in Reproductive Endocrinology at Massachusetts General Hospital, where she remained on faculty for 3 years prior to joining the faculty at New Jersey Medical School in 1988.

She helped recruit talent to make the University of Colorado’s Department of OB/GYN #8 in the country for NIH funding in 2017. Over the course of her career thus far, Dr. Santoro has personally mentored over 100 students, residents, postdoctoral fellows, and junior faculty, many of whom have gone on to illustrious academic careers.

An accomplished researcher, Dr. Santoro’s current exploration involves treatment of menopausal symptoms in women, understanding the mechanisms by which obesity causes relative infertility in women, participating in clinical trials in reproductive medicine, and research training of OB/GYNs and reproductive endocrinologists. Dr. Santoro worked closely with the former CU ARM laboratory, which specialized in the development and measurement of reproductive hormones using state-of-the-art methodologies.

Dr. Santoro has developed techniques to perform field studies that allow for daily hormone assessments without the inconvenience of blood drawing by using urine sampling. She is past Chair of the Steering Committee for the Reproductive Medicine Network, and current principal investigator with the CONFIRM network, both NIH-funded clinical trial networks devoted to the study of problems in human reproduction.

In addition to her extensive research, Dr. Santoro has authored over 300 peer-reviewed scientific publications and edited four books. Additionally, Dr. Santoro has held leadership positions with numerous professional organizations and is currently President-Elect of the Society for Reproductive Investigation. Among Dr. Santoro’s decorated career of achievements, she was elected to the National Academy of Medicine in 2018. Dr. Santoro has been named a Castle Connelly “Best Doctor” and “Best Doctor in America” as well as a “Best Doctor” by New York Magazine and “Top Doc” by 5280 Magazine.

Dr. Santoro sees SGF Colorado patients at the Denver office, while also maintaining her position at CU treating women for complex menopause management. Dr. Santoro will continue to provide training to the University of Colorado Reproductive Endocrinology and Infertility fellowship program.

Read More


  • Residency: Obstetrics and Gynecology, Beth Israel Medical Center
  • Fellowship: Reproductive Endocrinology and Infertility, Massachusetts General Hospital
  • Top Doctors, Castle Connolly (1999-2014, 2024)
  • Denver’s Top Doctors, 5280 Magazine (2016-2023)
  • Best Doctors, New York Magazine (2001, 2003-2006)
  • Best Doctors, Good Housekeeping Magazine (1997)
  • Mentor of the Year, Clinical Research Training Program, Albert Einstein College of Medicine (2006)
  • Best Doctor, Best Doctors in America (2008-2014)
  • Award for Outstanding Achievement in Women’s Health Research, Society for Women’s Health Research (2015)
  • Outstanding Mentor Award, Endocrine Society (2016)
  • Exceptional Women in Medicine by Castle Connolly (2023 – 2024)
  • American Association for Gynecologists and Obstetricians Foundation
  • American Board of Obstetrics and Gynecology, Inc.
  • American Gynecologic and Obstetrical Society
  • American Society for Reproductive Medicine
  • Endocrine Society
  • National Academy of Medicine
  • North American Menopause Society
  • Society for Reproductive Endocrinology and Infertility
  • Society for Reproductive Investigation

Coming Soon!


As a resident, I met several role models who helped further spark my interest in the field of reproductive endocrinology. It became clear to me that helping people create or expand their families was one of the most rewarding things I could possibly do with my life.

Reproduction is the most significant process that we do as humans. If reproduction does not work, that is the end of our species!

I feel that it’s most important to cultivate and maintain the understanding that I am a member of my patients’ team. I am on their side. There can be so much unbearable frustration involved in prolonged fertility treatment, and I feel it is important for me not to look away and to make sure my patients know I am with them for the duration of the journey, no matter the outcome.

As a child, I was obsessed with Marie Curie and read her biography over and over. I usually never read a book twice!

Scuba diving, hiking, and cooking.

I love nature and hiking in Colorado is one of the best ways to enjoy it. Scuba diving is like hiking but underwater – it offers same feeling but with more equipment! Also, who doesn’t love eating a delicious and beautifully presented meal with friends and family?

I’m a sunny optimist for sure.