Nicole P. Doyle, M.D., Ph.D.

Board Certified Board Certified

  • Obstetrics and Gynecology
  • Reproductive Endocrinology and Infertility

Languages Languages

  • English and German
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Nicole P. Doyle, M.D., Ph.D., FACOG, earned her medical degree and doctorate in philosophy from the Medical School of the Technical University of Munich and completed her residency training in Obstetrics and Gynecology at Georgetown University Hospital. Dr. Doyle went on to complete her fellowship in Reproductive Endocrinology and Infertility at the National Institutes of Health.

Dr. Doyle has published several peer-reviewed scientific manuscripts, book chapters, and review articles in many leading scientific journals in the fields of reproductive endocrinology and infertility. Her specific research interest is examining the timing for embryo transfer and she continues this work as a member of the research team at Shady Grove Fertility. She is a fellow of the American Congress of Obstetrics and Gynecology and a member of numerous medical organizations.

Dr. Doyle’s clinical interests include any aspect of female and male infertility, in particular optimizing outcomes in patients with diminished ovarian reserve or premature ovarian insufficiency; making advances in in vitro fertilization, oocyte donation, recurrent pregnancy loss, fertility preservation, and polycystic ovary syndrome (PCOS).

Dr. Doyle is married and together with her family she enjoys the outdoors, skiing, and spending time in Europe to visit family. Dr. Doyle is fluent in German and joined SGF in 2020.

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  • Residency: Obstetrics and Gynecology, Georgetown University Hospital
  • Fellowship: Reproductive Endocrinology and Infertility, National Institutes of Health
  • Washingtonian’s Top Doctors for Infertility (2023)
  • Reproductive Endocrinology and Infertility Award, Medstar Georgetown University Hospital
  • Excellence Award: Gynecologic Surgery, Medstar Washington Hospital Center
  • Research Award: Finalist Research Award. Medstar Health, Washington Hospital Center/Georgetown University Hospital
  • Teaching Award: Resident Teaching Award, Christiana Health Care, Delaware, USA
  • American Congress of Obstetricians and Gynecologists
  • American Society for Reproductive Medicine
  • Beste MT, Pfäffle-Doyle N, Prentice EA, Morris SN, Lauffenburger DA, Isaacson KB, Griffith LG. Molecular network analysis of endometriosis reveals a role for c-Jun-regulated macrophage activation. Sci Transl Med. 2014 Feb 5;6(222):222ra16.
  • Heider P, Pfäffle N, Pelisek J, Wildgruber M, Poppert H, Rudelius M, Eckstein HH. Is serum pregnancy-associated plasma protein A really a potential marker of atherosclerotic carotid plaque stability? Eur J Vasc Endovasc Surg. 2010; 39(6):668-75.
  • 2018 SRI: Eubanks A., Parikh T., Doyle N., DeCherney A., Healy M., Yauger B., Csokmay j., Hill M. Is the addition of vaginal estrace a risk factor for adverse obstetrical outcomes in frozen embryo transfers (FET)?
  • 2018 SRI: Doyle N., Eubanks A., Richter K., DeCherney A., O’Brien J. Advanced paternal age may be a minor contributor to aneuploidy risk in IVF conception.
  • 2018 PCRS: Doyle N., Doyle J., Stillman R., Tucker M., Graham J., Richter K., Decherney A., Levy M. Blastocyst freeze-all strategy versus fresh transfer in anonymous oocyte donation cycles.
  • ASRM 2017. Doyle N., Parikh T. Eubanks A., DeCherney A., Healy M., Yauger B., 1 , Csokmay J., Hill M. The effect of vaginal estradiol on live birth in preparation of the endometrium in FET cycles.
  • 2017 ASRM. Doyle N., DeCherney A., Levy M., Hill M. Freeze-all versus fresh transfer at the blastocyst stage in autologous and donor IVF cycles: A SART review.
  • ASRM 2017. Doyle N., Hill M., Caswell W., Lim J., Tucker M., Stratton M., Graham J., DeCherney A., Devine K., Hayes H., Levy M. PGS does not improve pregnancy outcomes in IVF cycles using vitrified donor oocytes.
  • ASRM 2017. Doyle N., Hill M., Caswell W., Lim J., Tucker M., Stratton M., Graham J., DeCherney A., Devine K., Hayes H., Levy M., Doyle J. Association between the number of retrieved mature donor oocytes and live birth in IVF donor recipient cycles using frozen donor eggs.
  • PCRS 2017. Doyle, N., Richter K., Hill M., Patounakis G., Tucker M., Doyle J., Levy M. Larger donor oocyte cohorts maximize potential number of live born infants per retrieval among recipient in vitro fertilization (IVF) patients.
  • ASRM 2015. Doyle, N., Patounakis G., Han T., Stillman R., DeCherney A., Richter K. Too much of a good thing? High motile sperm concentrations may reduce conventional insemination in vitro fertilization (CI-IVF) birth.
  • ASRM 2014. Doyle, N., Richter, K. Bromer, J., Hill, M., Graham, J. Tucker, M., Stillman, R. Blastocyst quality can select older patients up to and including 40 years of age for successful elective single embryo transfer (eSET).
  • SMFM 2013. Ruhstaller, K., Hoffman, M., Sciscione, A., Doyle, N. Does maternal BMI impact the rate of preterm birth in women receiving 17-OH progesterone?
  • SGI 2011. Doyle, N., Beste, M., Joughin, B., Lauffenburger, D., Isaacson, K., Griffith, L. Quantitative Methods for Detecting and Characterizing Endometrial Epithelial and Stromal Cells in Peritoneal Fluid From Patients With Endometriosis.
  • BMES 2010. Doyle, N., Beste, M., Joughin, B., Lauffenburger, D., Isaacson, K., Griffith, L. Towards an ex vivo model of lesion formation in endometriosis.
  • BMES 2010. Beste, M., Doyle, N., Starzinski-Powitz, A., Lauffenburger, D., Isaacson, K., Griffith, L. Identifying Potential Roles for EGFR Family Cross-Talk During Lesion Formation in Endometriosis.
  • Book Chapter Doyle N., Banks N., and Wolff E. Chapter 10: Mechanisms of primary ovarian insufficiency in Primary Ovarian Insufficiency: A Clinical Guide to Early Menopause. Springer 2016.
  • Doyle N., Doyle J., DeCherney A. Is it good practice/ethical to set a max BMI before IVF? Emerging Topics in Reproduction, Volume 5. Springer 2018.


I remember my anatomy professor in medical school asking my class of 400 students this question on my very first day of lectures. He handed out a shred of paper and had us write down the reason we were starting on this long journey of training asking us to keep this little note throughout our careers. On mine is written “fascination human being.” It sits in a little box on my desk, but I never had to take it out as a reminder since that first day in medical school. The human body has never failed to amaze and fascinate me. Fascination for something I do the majority of my week provides a good foundation to find fulfillment and joy in my work. I do not dread a Monday morning.

The goal of all efforts in reproductive endocrinology is to help someone have a healthy baby and, to me, being a small part at the very beginning of a new family is a very meaningful experience. I also enjoy being a part of a relatively young, but fast evolving field in medicine that constantly finds new scientific discoveries.

People from all walks of life inspire me. Great minds with humble attitudes inspire me. During my postdoctoral fellowship, residency, and my fellowship in reproductive endocrinology and infertility, I was fortunate to meet some of the highest regarded scientists in the world. Their heartfelt passion and curiosity is contagious and lights a spark in others to push the frontiers in science. My patients inspire me, as they go through a difficult time in their lives, they push for what is important for them with endless perseverance, optimism, and strength, and I consider it a privilege and honor to be by their side every step of the way. My children inspire me with their thirst to discover the world.

As a physician and mother of small children, my first thought to this question was, “what is spare time?” But reflecting more on this, I do realize I still enjoy a variety of activities. I am an avid skier and love the combination of physical exhaustion and fresh air. One day, I hope to make it through the first series of Ashtanga yoga, though I may break a limb on the way. I enjoy a fresh crusty loaf of homemade bread and even keep my own sourdough. I also cherish long weekend hikes with my family, cut off from the rest of the world. These hikes do spark the best conversations between my husband and me.

I completed my OB/GYN residency training at Georgetown Medical University Hospital and fellowship in reproductive endocrinology at the National Institutes of Health. Both institutes send their students to SGF to be trained and so I feel that over the last several years, I have had a unique opportunity to obtain an inside perspective of the philosophy and mechanics that drive the accomplishments of SGF. I firmly believe that the essence of practicing good medicine lies in genuine desire and devotion to delivering the highest quality of medical care through knowledge, strong clinical judgment, compassion, and dedicated support of the patient. This is the fundamental base that allows us to excel at what we do every day. Early on in my training, it was obvious to me that SGF stands for these qualities and that the achievements of the practice were the result of dedication and hard work by many. I wanted to be a part of their team ever since.

As much as I enjoy the anticipation of the many bullet points on my bucket list, I try to put equal emphasis on living in the moment and reflect on the things I was already fortunate enough to cross off my list of goals. In our fast paced lives it seems sometimes more challenging to reflect on our many blessings than to add more to our wish lists. That being said, I do hope that I will get to write a children’s book one day, travel all seven continents with my family, and go back to the hotel my husband and I spent the last day of our honeymoon.

Honesty, thorough counseling, transparency, empathy, and attentive listening have always worked for my patients and me. There is no one approach for a struggling patient, but rather a personalized strategy for each patient at each step of the way. For some a gentle push is needed, for others stopping or a break from treatment might be indicated. A solid physician-patient rapport is the basis to finding the right solution for every patient.