Our Office is nearest to you Not your office?

Isaac E. Sasson, M.D., Ph.D.

Medical Director, Pennsylvania

Board Certified

  • Obstetrics and Gynecology
  • Reproductive Endocrinology and Infertility
945 Chesterbrook Boulevard
Chesterbrook, PA 19087
Leave a Review Schedule with Dr. Sasson
Find out what's possible
New Patient Appointments or 1.888.761.1967

About isaac e. sasson, M.D., ph.d.

Isaac E. Sasson, M.D., Ph.D., FACOG, received his medical degree and doctorate in genetics from Yale Medical School. He went on to complete his residency in obstetrics and gynecology at Yale-New Haven Hospital and his subspecialty training in reproductive endocrinology and infertility at the Hospital of the University of Pennsylvania in Philadelphia.

He has expertise in the diagnosis and treatment of infertility, including in vitro fertilization, donor egg treatment, endometriosis, polycystic ovary syndrome, and preimplantation genetic diagnosis. He utilizes both his clinical experience and extensive background in genetics research to optimize patient pregnancy and live birth rates.

Dr. Sasson has been featured in many publications, including Main Line Parent, Philadelphia Life, and Suburban Life. He has also appeared on The Katie Couric Show in a segment highlighting male factor infertility and on CBS 3 Philadelphia, where he discussed technological advancements in fertility treatment.

Originally from Monmouth County, New Jersey, Dr. Sasson is married with three children and enjoys yoga, spinning, hiking, and woodworking.

Dr. Sasson is currently associate residency director of ob-gyn residents at Lankenau Hospital outside of Philadelphia. He is a member of the American Society for Reproductive Medicine, American Congress of Obstetricians and Gynecologists, Obstetrical Society of Philadelphia, and Philadelphia Area Reproductive Endocrine Society.

  • Residency: Obstetrics and Gynecology, Yale-New Haven Hospital
  • Fellowship: Reproductive Endocrinology and Infertility, University of Pennsylvania
Awards & Recognition
  • 2016 Inaugural Physicians Council Member, RESOLVE The Infertility Association
  • Main Line Today magazine Top Doctors (2014-2015)
  • Suburban Life magazine (August 2016)
Professional Organizations
  • American Congress of Obstetricians and Gynecologists
  • American Society of Reproductive Medicine
  • Obstetrical Society of Philadelphia
  • Philadelphia Area Reproductive Endocrine Society

Q & A

Q: Why did you become a doctor?


My father is a pediatrician and the practice of medicine was always in our home. He works very hard, and growing up I always heard him on the phone with patients. He served as a role model when becoming an adult. So my connection to medicine is very connected to my family life at home.

Q: Who inspires you?


I am inspired by my patients’ strength. I am inspired by my kids’ thirst for knowledge, love, and experience. I am inspired by my medical school classmates. I am regularly amazed at how diverse they are and how much they have accomplished. I am inspired by the nursing staff at Shady Grove Fertility who are on the front line of patient care and are always working for perfection. I am inspired by my best friend, a lawyer on Capitol Hill. He is full of energy and enthusiasm and always looking for the next meaningful life experience. I think he is acutely aware that we only live once and that we need to make the most of every single day.

Q: What’s on your bucket list?


I want to lie on a beach in Tahiti, dive on the Great Barrier Reef, and go on safari in Africa.

Q: What are your hobbies?


I enjoy woodworking, yoga, and spinning.

Q: What about you would most surprise people?


I come from a big family; I am the oldest of six. When my wife and I tried to expand our family we turned to treatment and we now have twins from an injectable cycle. At the time, no one told me there was a 20 percent risk of twins. It makes me acutely sensitive to patients that say “I’m okay with twins.”

Q: What about SGF makes you the most proud?


I think we do an amazing job at providing quality, evidence-based care, with attention to service and personalized to a patient’s needs.

I am inspired by the nursing staff at Shady Grove Fertility who are on the front line of patient care and are always working for perfection.


"I cannot express how confident I feel in recommending Dr. Sasson and his team/staff at Shady Grove Fertility. They went above and beyond to make our struggle less stressful. They truly eased the burden and guided us to a path of accepting our struggles and developed a plan that made the most sense for us. Not only were they informative and patient, but they were professional and available in every encounter. I am 100% pleased with my experience, and again, would recommend Shady Grove Fertility to anyone who is having challenges with infertility. Thank you SGF!"

"I have been to two other fertility clinic's in the area. My experience with Dr. Sasson and Shady Grove Fertility has been a night and day difference. Dr. Sasson makes you feel immediately comfortable and optimistic. You do not feel like a just another patient. You are assigned your own nurse who will be your point person to ask any questions to. My nurse Lisa was amazing. If I could have Shady Grove Fertility and Dr. Sasson monitor my whole pregnancy I would!"

"Dr. Sasson and his team are simply amazing! He is kind, compassionate, patient, and extremely good at what he does. I spent 1 year under his care, and during that time he NEVER gave up on me, even when I wanted to give up on myself. He, along with my nurses, became my family and support system through it all. He personally tailored every protocol to fit my needs, and was with me every step of the way through my journey. I am now 14 weeks pregnant, and couldn’t have done it without Dr Sasson!"

"Dr. Sasson changed our lives and made our dreams come true! I had been to another facility and they could not identify the real issue for a year! We went from being very pessimistic to being highly optimistic after just 2 meetings with Dr. Sasson. We had our first consultation with Dr. Sasson in March and we conceived through IVF in July! It’s not just him but the entire staff at Shady Grove Fertility that is very caring and extremely friendly. Strongly recommend this place."

"I came to Dr. Sasson after failed fertility treatment at a different clinic. And not only did I receive different (and better) medical treatment, but I also received far better care. Everyone at SGF Chesterbrook really cared, it was evident in how long they discussed things with me, how they always took my calls/answered my emails (Nikki, my nurse, never let 24 hours go by without responding!) and how they were always there when I needed a shoulder to cry on. Even the receptionist was always friendly and go out of her way to chat, it definitely eased my waiting room anxiety. They were truly invested with me and my husband. I can happily say that after one round of IVF with Shady Grove Fertility, I became pregnant and am 3.5 months along. When they called to tell me the good news, I could genuinely feel how happy they were for me. It was bittersweet leaving SGF for sure. I can’t recommend them enough."

"We will be eternally grateful for finding our way to Dr. Sasson on our journey with infertility. After having multiple failed treatments with a different practice that left us feeling hopeless, walking into our initial consultation with Dr. Sasson was like a breath of fresh air-we immediately knew we were in great hands with practice, who approach patient care as a team. We received compassionate, expert care from Dr. Sasson and his colleagues. I could not more highly recommend this physician!"

"Dr. Sasson and his team at Shady Grove Fertility are simply amazing! I can honestly say that Dr. Sasson is the kindest, caring, and most compassionate doctor I have ever had. He personally called me on multiple occasions to deliver both bad and good news, and he was always accessible by email when I needed him. He was encouraging, and never gave up on me, even when I wanted to give up on myself. After my first IVF cycle failed, he even stayed late on a Saturday to meet with my husband and me to regroup and go over plans for the next one. He tailored a protocol that was specific to me, and I’m happy to say that I’m currently 8 weeks pregnant! My nurses Erica and Lisa were also fantastic! They always made me feel like a priority, and they were truly invested in our success. Dr. Sasson and his team became my family, and I will miss them now that I see my regular OBGYN. If you are considering a fertility doctor in this area, I wouldn’t go anywhere else!"

"I had the best experience with Shady Grove and Dr. Sasson. I felt so supported and they never make you feel like you are overreacting or being crazy. Nikki my nurse was lovely. I miss them now that I go to the regular OBGYN. My husband and I always comment that it is the best doctor experience we have ever had. We felt like VIPs and always wonder why other medical experiences can’t be so supportive and positive. Any people who need fertility help this is the practice to go to."



  • Sasson IE, Vitins AP, Mainigi MA, Moley KH, Simmons RA. Pre-gestational vs. gestational exposure to maternal obesity differentially programs the offspring in mice. Diabetologia. 2015;58:615-624.
  • Grissom NM, Lyde R, Christ L, et al. Obesity at conception programs the opioid system in the offspring brain. Neuropsychopharmacology. 2014;39:801-810.
  • Sasson I, Mesaros C, Bartolomei MS. Bisphenol A exposure alters DNA methylation and disrupts genomic imprinting in the mouse. PLoS Genetics. 2013;9:e1003401.
  • Guzeloglu-Kayisli O, Lalioti MD, Aydiner F, et al. Embryonic poly(A) binding protein (EPAB) is required for oocyte maturation and female fertility in mice. Biochem J. 2012;446:47-58.
  • Sasson IE, Kodaman PH. Adhesion prevention in gynecologic surgery. The Female Patient. 2008;33:1-5.
  • Johnson LN, Sasson IE, Sammel MD, Dokras A. Does intracytoplasmic sperm injection improve the fertilization rate and decrease the total fertilization failure rate in couples with well-defined unexplained infertility? A systematic review and meta-analysis. Fertil Steril. 2013;100:704-11.
Resources and Events

Recently Visited Pages

The following mark the 9 most recent pages you have visited on ShadyGroveFertility.com. Please click a link below to return to that page.